Across TCGA pan-cancer cohorts, NT5M mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated NT5M data layer compared with 24 for mass-spec protein and 3 for mutation status.
The strongest signal is observed in glioblastoma multiforme (GBM), where higher NT5M mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NT5M expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.
GBM are the cancer types where NT5M mass-spec protein most reproducibly stratifies survival.