NT5DC3

Across TCGA pan-cancer cohorts, NT5DC3 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated NT5DC3 data layer compared with 24 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher NT5DC3 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated NT5DC3 expression acts as an unfavorable survival marker.

PDAC, LUAD, and CCRCC are the cancer types where NT5DC3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	All	0.194	0.374	.001	80	view →
LUAD	DFS	Median	All	0.498	0.753	.006	7	view →
CCRCC	DFS	Median	All	0.726	0.896	.016	5	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

NT5DC3–PDAC (DFS)

Open the PDAC breakdown →