NT5DC2

Across TCGA pan-cancer cohorts, NT5DC2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NT5DC2 data layer compared with 26 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher NT5DC2 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated NT5DC2 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

LSCC, UCEC, and LUAD are the cancer types where NT5DC2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Tertile	II,III,IV	0.867	0.495	.007	24	view →
UCEC	DFS	Median	All	0.785	0.927	.021	12	view →
LUAD	OS	Quartile	All	0.482	0.899	.019	3	view →
HNSC	OS	Tertile	All	0.640	0.839	.038	2	view →
CCRCC	OS	Median	II,III,IV	0.554	1.000	.025	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NT5DC2–LSCC (OS)

Open the LSCC breakdown →