NT5DC2

Across TCGA patient cohorts, NT5DC2 mutation is significantly associated with the RNA expression of many other genes, with 571 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NT5DC2-associated genes across cancer lineages are PLCE1P1, MRPS6P4, and RCC2P5. Each is linked with NT5DC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NT5DC2-to-partner and partner-to-NT5DC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PLCE1P1 grouped by NT5DC2-low versus NT5DC2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NT5DC2→partner) and Y-score (partner→NT5DC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PLCE1P1 →	+0.239	+7.731	<.001	.009	3	2
COAD	MRPS6P4 →	+0.270	+3.917	<.001	.009	3	2
SKCM	RCC2P5 →	+0.053	+3.328	<.001	<.001	3	2
BRCA	RN7SKP221 →	+0.099	+8.471	<.001	.005	3	2
COAD	RNU4-79P →	+0.182	+4.734	<.001	.002	3	2
COAD	RNA5SP378 →	+0.542	+3.496	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 571 associations by consensus.

PLCE1P1 by NT5DC2 expression — BRCA

Explore this box plot interactively →