NT5DC2

Across TCGA patient cohorts, NT5DC2 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NT5DC2-associated genes across cancer lineages are ASNS, HER3_pY1289, and p38-MAPK_pT180_Y182. Each is linked with NT5DC2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NT5DC2-to-partner and partner-to-NT5DC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by NT5DC2-low versus NT5DC2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NT5DC2→partner) and Y-score (partner→NT5DC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ASNS →	+0.816	+2.815	<.001	.036	3	3
COAD	HER3_pY1289 →	+0.130	+2.832	.013	.035	3	1
COAD	p38-MAPK_pT180_Y182 →	+0.471	+2.832	.049	.035	3	1
COAD	Caspase-7-cleavedD198 →	+1.387	+2.815	.001	.036	1	3
COAD	4E-BP1_pT70 →	+0.176	+2.815	.007	.036	3	1
UCEC	N-Ras →	-0.137	-1.986	.010	.032	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

ASNS by NT5DC2 expression — COAD

Explore this box plot interactively →