NT5DC2

Across TCGA cell cohorts, NT5DC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,120 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible NT5DC2-associated GO terms across cancer lineages are Negative regulation of dopamine metabolic process, DNA replication checkpoint signaling, and Nuclear chromosome segregation. Each is linked with NT5DC2 in more than 13 cancer types. Because this analysis shows association rather than direction, both NT5DC2-to-partner and partner-to-NT5DC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of dopamine metabolic process grouped by NT5DC2-low versus NT5DC2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NT5DC2→partner) and Y-score (partner→NT5DC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of dopamine metabolic process →	+0.375	+1.377	.002	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	DNA replication checkpoint signaling →	+0.170	+1.403	<.001	<.001	2	14
OESOPHAGUS	Nuclear chromosome segregation →	+0.126	+1.137	.009	.001	2	13
URINARY_TRACT	Regulation of metaphase/anaphase transition of cell cycle →	+0.128	+1.313	.001	.001	3	12
URINARY_TRACT	Regulation of mitotic metaphase/anaphase transition →	+0.131	+1.351	.001	.001	3	12
OESOPHAGUS	Protein-DNA complex disassembly →	+0.138	+0.867	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,120 associations by consensus.

Negative regulation of dopamine metabolic process by NT5DC2 expression — OESOPHAGUS

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