NT5DC2

Across TCGA cell cohorts, NT5DC2 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NT5DC2-associated genes across cancer lineages are VCY1B, VCY, and TRAT1. Each is linked with NT5DC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NT5DC2-to-partner and partner-to-NT5DC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VCY1B grouped by NT5DC2-low versus NT5DC2-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NT5DC2→partner) and Y-score (partner→NT5DC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	VCY1B →	+0.294	+4.029	<.001	.009	3	1
OVARY	VCY →	+0.297	+4.228	<.001	.006	3	1
OVARY	TRAT1 →	+0.017	+4.029	.005	.009	3	1
LUNG_NSCLC_LUAD	BPY2 →	+0.006	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	BPY2B →	+0.006	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	BPY2C →	+0.006	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

VCY1B by NT5DC2 expression — OVARY

Explore this box plot interactively →