NT5DC1

Across TCGA pan-cancer cohorts, NT5DC1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated NT5DC1 data layer compared with 24 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher NT5DC1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated NT5DC1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and LUAD show a favorable association.

PDAC, CCRCC, and HNSC are the cancer types where NT5DC1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Quartile	All	0.750	0.338	.005	46	view →
CCRCC	DFS	Quartile	All	0.435	0.908	.001	24	view →
HNSC	DFS	Median	III,IV	0.897	1.000	.002	18	view →
COAD	DFS	Median	III,IV	0.828	1.000	.025	12	view →
LUAD	OS	Tertile	II,III,IV	0.871	0.300	.012	10	view →
GBM	DFS	Tertile	All	0.464	0.238	.040	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

NT5DC1–PDAC (OS)

Open the PDAC breakdown →