NT5DC1

Across TCGA patient cohorts, NT5DC1 mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NT5DC1-associated genes across cancer lineages are JNK2, ASNS, and EGFR_pY1068. Each is linked with NT5DC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NT5DC1-to-partner and partner-to-NT5DC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK2 grouped by NT5DC1-low versus NT5DC1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NT5DC1→partner) and Y-score (partner→NT5DC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.220	+2.196	.002	.032	3	2
UCEC	ASNS →	+0.563	+2.700	<.001	.005	3	2
UCEC	EGFR_pY1068 →	-0.273	-2.321	.003	.005	3	1
UCEC	eIF4G →	+0.329	+3.459	.003	.005	3	1
UCEC	A-Raf_pS299 →	-0.149	-1.807	<.001	.025	3	1
UCEC	ERK2 →	+0.207	+3.321	.003	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

JNK2 by NT5DC1 expression — UCEC

Explore this box plot interactively →