NT5C3B

Across TCGA pan-cancer cohorts, NT5C3B mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NT5C3B data layer compared with 27 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher NT5C3B mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated NT5C3B expression acts as an unfavorable survival marker.

CCRCC, OV, and LSCC are the cancer types where NT5C3B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	0.822	0.956	.005	14	view →
OV	DFS	Median	All	0.847	1.000	.019	8	view →
LSCC	DFS	Quartile	III,IV	0.604	0.970	.047	4	view →
PDAC	DFS	Quartile	All	0.665	0.784	.013	3	view →
HNSC	DFS	Tertile	III,IV	0.912	1.000	.033	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NT5C3B–CCRCC (OS)

Open the CCRCC breakdown →