Across TCGA pan-cancer cohorts, NT5C3AP1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of NT5C3AP1’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where NT5C3AP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NT5C3AP1 is over-expressed in tumor.
KIRC, LIHC, and CHOL are the cancer types where NT5C3AP1 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NT5C3AP1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.