NT5C3A

Across TCGA pan-cancer cohorts, NT5C3A mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NT5C3A data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher NT5C3A mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated NT5C3A expression acts as an unfavorable survival marker, although some lineages such as HNSC and PDAC show a favorable association.

LUAD, HNSC, and PDAC are the cancer types where NT5C3A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	All	0.427	0.872	<.001	16	view →
HNSC	OS	Tertile	IV	0.866	0.544	.006	9	view →
PDAC	OS	Median	III,IV	0.590	0.328	.019	8	view →
UCEC	DFS	Tertile	All	0.945	0.831	.034	8	view →
LSCC	OS	Median	III,IV	0.566	0.908	.021	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NT5C3A–LUAD (DFS)

Open the LUAD breakdown →