NT5C2

Across TCGA patient cohorts, NT5C2 mutation is significantly associated with the RNA expression of many other genes, with 3,126 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NT5C2-associated genes across cancer lineages are BNIP3P2, LINC02559, and RNU7-4P. Each is linked with NT5C2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NT5C2-to-partner and partner-to-NT5C2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BNIP3P2 grouped by NT5C2-low versus NT5C2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NT5C2→partner) and Y-score (partner→NT5C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	BNIP3P2 →	+0.045	+4.837	<.001	.003	3	2
CESC	LINC02559 →	+1.060	+4.342	<.001	.007	3	2
CESC	RNU7-4P →	+0.281	+4.342	<.001	.007	3	2
CESC	GRAMD4P6 →	+0.074	+5.164	<.001	.002	3	2
CESC	H3Y1 →	+1.374	+4.016	<.001	.001	3	2
CESC	MBD3L3 →	+0.277	+4.144	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,126 associations by consensus.

BNIP3P2 by NT5C2 expression — CESC

Explore this box plot interactively →