Across TCGA patient cohorts, NT5C1B mutation is significantly associated with the RNA expression of many other genes, with 3,381 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NT5C1B-associated genes across cancer lineages are MED27, POC1A, and SAP30. Each is linked with NT5C1B in more than 2 cancer types. Because this analysis shows association rather than direction, both NT5C1B-to-partner and partner-to-NT5C1B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NT5C1B→partner) and Y-score (partner→NT5C1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MED27 →	+0.333	+1.701	<.001	<.001	3	3
UCEC	POC1A →	+0.494	+2.475	.001	<.001	3	3
UCEC	SAP30 →	+0.504	+1.658	<.001	.001	3	3
UCEC	CENPX →	+0.439	+2.491	<.001	<.001	3	3
UCEC	RASSF1 →	+0.347	+2.321	<.001	.001	3	3
UCEC	ENO1 →	+0.391	+2.475	.007	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,381 associations by consensus.

Exploration

NT5C1B survival (RNA) · tumor vs normal (RNA) · all NT5C1B data types