NT5C1B-RDH14

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NT5C1B-RDH14 RNA expression is significantly associated with the go_rna of many other GO terms, with 476 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible NT5C1B-RDH14-associated GO terms across cancer lineages are Negative regulation of sprouting angiogenesis, Regulation of testosterone biosynthetic process, and Positive regulation of cardiac muscle cell differentiation. Each is linked with NT5C1B-RDH14 in more than 1 cancer types. Because this analysis shows association rather than direction, both NT5C1B-RDH14-to-partner and partner-to-NT5C1B-RDH14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of sprouting angiogenesis grouped by NT5C1B-RDH14-low versus NT5C1B-RDH14-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NT5C1B-RDH14→partner) and Y-score (partner→NT5C1B-RDH14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADNegative regulation of sprouting angiogenesis →-0.054-0.004.001.00131
STADRegulation of testosterone biosynthetic process →-0.050-0.003.003.00131
STADPositive regulation of cardiac muscle cell differentiation →-0.079-0.004<.001<.00131
BRCARegulation of dendrite extension →+0.034+0.003<.001.00131
BRCAPositive regulation of protein sumoylation →+0.023+0.003<.001<.00131
BRCARegulation of collateral sprouting →+0.023+0.002.002.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 476 associations by consensus.

Negative regulation of sprouting angiogenesis by NT5C1B-RDH14 expression — STAD

Box plot of Negative regulation of sprouting angiogenesis in NT5C1B-RDH14-low vs NT5C1B-RDH14-high samples in STAD.

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Exploration