NT5C1B-RDH14

Across TCGA cell cohorts, NT5C1B-RDH14 mutation is significantly associated with the RNA expression of many other genes, with 86 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NT5C1B-RDH14-associated genes across cancer lineages are RHOXF1, FNDC1, and INSL5. Each is linked with NT5C1B-RDH14 in more than 1 cancer types. Because this analysis shows association rather than direction, both NT5C1B-RDH14-to-partner and partner-to-NT5C1B-RDH14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RHOXF1 grouped by NT5C1B-RDH14-low versus NT5C1B-RDH14-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NT5C1B-RDH14→partner) and Y-score (partner→NT5C1B-RDH14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	RHOXF1 →	+0.339	+3.688	.007	.007	3	1
STOMACH	FNDC1 →	+0.042	+3.637	<.001	.008	3	1
STOMACH	INSL5 →	+0.105	+4.280	<.001	.001	3	1
STOMACH	TSPY10 →	+0.039	+3.794	<.001	.003	3	1
SKIN	FHL5 →	+0.073	+3.415	.007	.001	3	1
LUNG_NSCLC_LUAD	OR8B2 →	+0.071	+3.604	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 86 associations by consensus.

RHOXF1 by NT5C1B-RDH14 expression — STOMACH

Explore this box plot interactively →