NT5C1A

Across TCGA pan-cancer cohorts, NT5C1A Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated NT5C1A data layer compared with 15 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in kidney chromophobe (KICH), where higher NT5C1A Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated NT5C1A expression acts as an unfavorable survival marker, although some lineages such as STAD show a favorable association.

KICH, UCEC, and READ are the cancer types where NT5C1A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Median	All	0.102	0.848	.004	13	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
READ	OS	Median	All	0.281	0.830	.006	3	view →
STAD	OS	Median	IV	1.000	0.299	.047	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

NT5C1A–KICH (DFS)

Open the KICH breakdown →