NT5C1A

Across TCGA pan-cancer cohorts, NT5C1A mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated NT5C1A data layer compared with 15 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher NT5C1A mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated NT5C1A expression acts as an unfavorable survival marker, although some lineages such as CCRCC and GBM show a favorable association.

CCRCC, GBM, and LUAD are the cancer types where NT5C1A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	0.901	0.427	.009	12	view →
GBM	DFS	Median	All	0.805	0.632	.002	7	view →
LUAD	DFS	Median	All	0.748	0.439	.011	3	view →
HNSC	OS	Median	II,III,IV	0.946	0.811	.024	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

NT5C1A–CCRCC (OS)

Open the CCRCC breakdown →