NT5C1A

Across TCGA cell cohorts, NT5C1A mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible NT5C1A-associated genes across cancer lineages are OR9A2, ZSCAN1, and MRAP. Each is linked with NT5C1A in more than 1 cancer types. Because this analysis shows association rather than direction, both NT5C1A-to-partner and partner-to-NT5C1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR9A2 grouped by NT5C1A-low versus NT5C1A-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NT5C1A→partner) and Y-score (partner→NT5C1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR9A2 →	+0.018	+5.209	<.001	.005	3	2
PANCREAS	ZSCAN1 →	+0.039	+5.000	<.001	.006	3	1
UPPER_AERODIGESTIVE_TRACT	MRAP →	+0.028	+4.736	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR12D3 →	+0.035	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR14C36 →	+0.020	+6.266	<.001	<.001	3	1
LUNG_NSCLC_LUAD	IQCF3 →	+0.042	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

OR9A2 by NT5C1A expression — BLOOD_Lymphoma

Explore this box plot interactively →