NT5C

Across TCGA pan-cancer cohorts, NT5C Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated NT5C data layer compared with 21 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher NT5C Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated NT5C expression acts as an unfavorable survival marker.

COAD, HNSC, and UCEC are the cancer types where NT5C Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	0.231	0.690	.014	15	view →
HNSC	OS	Median	All	0.191	0.751	.003	12	view →
UCEC	OS	Median	III,IV	0.061	0.588	.018	12	view →
LGG	OS	Median	All	0.374	0.799	.037	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

NT5C–COAD (DFS)

Open the COAD breakdown →