NSUN4

Across TCGA cell cohorts, NSUN4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,935 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NSUN4-associated GO terms across cancer lineages are Mitochondrial RNA catabolic process, Ribosomal large subunit assembly, and Mitochondrial large ribosomal subunit assembly. Each is linked with NSUN4 in more than 17 cancer types. Because this analysis shows association rather than direction, both NSUN4-to-partner and partner-to-NSUN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial RNA catabolic process grouped by NSUN4-low versus NSUN4-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NSUN4→partner) and Y-score (partner→NSUN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Mitochondrial RNA catabolic process →	+0.122	+1.032	<.001	<.001	3	18
BLOOD_Lymphoma	Ribosomal large subunit assembly →	+0.119	+0.638	<.001	.006	3	16
BONE	Mitochondrial large ribosomal subunit assembly →	+0.135	+0.813	<.001	.001	3	14
BONE	Metaphase/anaphase transition of cell cycle →	+0.207	+0.726	<.001	<.001	3	14
BONE	Metaphase/anaphase transition of mitotic cell cycle →	+0.193	+0.726	.001	<.001	3	14
LIVER	Pre-miRNA processing →	+0.088	+0.562	.006	.008	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,935 associations by consensus.

Mitochondrial RNA catabolic process by NSUN4 expression — SOFT_TISSUE

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