NSUN3

Across TCGA cell cohorts, NSUN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,954 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NSUN3-associated GO terms across cancer lineages are tRNA wobble cytosine modification, Double-strand break repair via nonhomologous end joining, and Receptor localization to non-motile cilium. Each is linked with NSUN3 in more than 18 cancer types. Because this analysis shows association rather than direction, both NSUN3-to-partner and partner-to-NSUN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA wobble cytosine modification grouped by NSUN3-low versus NSUN3-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NSUN3→partner) and Y-score (partner→NSUN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	tRNA wobble cytosine modification →	+0.112	+1.085	.006	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via nonhomologous end joining →	+0.064	+0.865	<.001	<.001	3	14
OESOPHAGUS	Receptor localization to non-motile cilium →	+0.154	+0.601	.001	.003	3	13
OESOPHAGUS	Protein localization to ciliary membrane →	+0.086	+0.628	.006	.004	3	12
STOMACH	Ubiquitin-dependent protein catabolic process via the N-end rule pathway →	+0.087	+0.592	.001	.002	3	11
LUNG_SCLC	Error-prone translesion synthesis →	+0.103	+0.709	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,954 associations by consensus.

tRNA wobble cytosine modification by NSUN3 expression — OESOPHAGUS

Explore this box plot interactively →