NSRP1

Across TCGA pan-cancer cohorts, NSRP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated NSRP1 data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher NSRP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated NSRP1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PDAC show a favorable association.

OV, CCRCC, and HNSC are the cancer types where NSRP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Tertile	All	0.456	1.000	.025	16	view →
CCRCC	DFS	Median	All	0.535	1.000	.002	14	view →
HNSC	DFS	Tertile	IV	0.455	0.731	.010	8	view →
LUAD	OS	Tertile	III,IV	1.000	0.534	.013	5	view →
PDAC	DFS	Tertile	III,IV	0.797	0.294	.007	3	view →
LSCC	OS	Tertile	All	0.848	0.921	.041	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

NSRP1–OV (DFS)

Open the OV breakdown →