NSMF

Across TCGA pan-cancer cohorts, NSMF Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated NSMF data layer compared with 26 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher NSMF Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated NSMF expression acts as an unfavorable survival marker.

HNSC, COAD, and ACC are the cancer types where NSMF Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.162	0.685	.018	24	view →
COAD	DFS	Median	All	0.165	0.692	<.001	15	view →
ACC	DFS	Median	All	0.089	0.666	.017	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

NSMF–HNSC (OS)

Open the HNSC breakdown →