NSMF

Across TCGA patient cohorts, NSMF mutation is significantly associated with the RNA expression of many other genes, with 939 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NSMF-associated genes across cancer lineages are RNA5SP198, MTATP6P21, and RN7SKP298. Each is linked with NSMF in more than 1 cancer types. Because this analysis shows association rather than direction, both NSMF-to-partner and partner-to-NSMF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP198 grouped by NSMF-low versus NSMF-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NSMF→partner) and Y-score (partner→NSMF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNA5SP198 →	+0.346	+5.729	<.001	<.001	3	2
UCEC	MTATP6P21 →	+0.237	+2.060	<.001	.002	3	2
SKCM	RN7SKP298 →	+0.316	+7.816	<.001	.008	3	1
UCEC	CCL5 →	+1.085	+2.269	.001	.001	3	1
UCEC	ZNHIT3 →	+0.384	+3.660	.005	.001	3	1
UCEC	TAF9 →	+0.591	+3.480	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 939 associations by consensus.

RNA5SP198 by NSMF expression — CESC

Explore this box plot interactively →