NSMF

Across TCGA cell cohorts, NSMF RNA expression is significantly associated with the go_rna of many other GO terms, with 3,988 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NSMF-associated GO terms across cancer lineages are Transcription pausing by RNA polymerase II, CTP salvage, and Pre-mRNA catabolic process. Each is linked with NSMF in more than 13 cancer types. Because this analysis shows association rather than direction, both NSMF-to-partner and partner-to-NSMF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription pausing by RNA polymerase II grouped by NSMF-low versus NSMF-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NSMF→partner) and Y-score (partner→NSMF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Transcription pausing by RNA polymerase II →	+0.156	+1.475	<.001	.003	3	14
LUNG_SCLC	CTP salvage →	+0.102	+0.938	<.001	<.001	3	12
BONE	Pre-mRNA catabolic process →	+0.187	+0.984	<.001	<.001	3	11
SOFT_TISSUE	Transcription initiation at RNA polymerase I promoter →	+0.109	+0.931	.001	.003	3	11
BONE	Transcription initiation at RNA polymerase III promoter →	+0.092	+0.936	.006	.003	2	12
OVARY	Cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.118	+1.126	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,988 associations by consensus.

Transcription pausing by RNA polymerase II by NSMF expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →