Across TCGA patient cohorts, NSMCE3 mutation is significantly associated with the RNA expression of many other genes, with 390 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NSMCE3-associated genes across cancer lineages are RNA5SP416, KRTAP8-2P, and MIR98. Each is linked with NSMCE3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NSMCE3-to-partner and partner-to-NSMCE3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NSMCE3→partner) and Y-score (partner→NSMCE3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP416 →	+0.758	+2.961	<.001	.002	3	2
SKCM	KRTAP8-2P →	+0.535	+6.080	<.001	.002	3	2
UCEC	MIR98 →	+0.424	+2.994	<.001	.003	3	1
UCEC	HERC2P2 →	+1.085	+3.343	<.001	.005	3	1
UCEC	RNA5SP411 →	+1.525	+2.656	<.001	.003	3	1
UCEC	BTBD10 →	+0.631	+3.202	.003	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 390 associations by consensus.

Exploration

NSMCE3 survival (RNA) · tumor vs normal (RNA) · all NSMCE3 data types