NSMCE1

Across TCGA cell cohorts, NSMCE1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,230 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NSMCE1-associated GO terms across cancer lineages are Regulation of leukocyte apoptotic process, Regulation of Golgi inheritance, and Interleukin-34-mediated signaling pathway. Each is linked with NSMCE1 in more than 6 cancer types. Because this analysis shows association rather than direction, both NSMCE1-to-partner and partner-to-NSMCE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of leukocyte apoptotic process grouped by NSMCE1-low versus NSMCE1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NSMCE1→partner) and Y-score (partner→NSMCE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Regulation of leukocyte apoptotic process →	-0.070	-0.929	.001	.002	3	6
BLOOD_Myeloma	Regulation of Golgi inheritance →	+0.142	+0.815	.004	.005	2	7
BLOOD_Lymphoma	Interleukin-34-mediated signaling pathway →	+0.078	+0.519	<.001	<.001	3	6
LUNG_NSCLC_LUSC	UMP metabolic process →	+0.144	+0.877	.001	.008	3	6
STOMACH	Purine-containing compound biosynthetic process →	+0.062	+0.676	.002	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	Pyrimidine nucleoside triphosphate catabolic process →	+0.129	+0.762	.008	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,230 associations by consensus.

Regulation of leukocyte apoptotic process by NSMCE1 expression — BLOOD_Myeloma

Explore this box plot interactively →