NSMAF

Across TCGA cell cohorts, NSMAF RNA expression is significantly associated with the go_rna of many other GO terms, with 3,954 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NSMAF-associated GO terms across cancer lineages are Regulation of hippo signaling, Microtubule polymerization or depolymerization, and SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Each is linked with NSMAF in more than 11 cancer types. Because this analysis shows association rather than direction, both NSMAF-to-partner and partner-to-NSMAF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of hippo signaling grouped by NSMAF-low versus NSMAF-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NSMAF→partner) and Y-score (partner→NSMAF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of hippo signaling →	+0.093	+1.126	.003	<.001	3	12
LARGE_INTESTINE	Microtubule polymerization or depolymerization →	+0.096	+0.752	<.001	<.001	3	11
PANCREAS	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process →	+0.050	+0.976	.002	<.001	3	11
STOMACH	Microtubule polymerization →	+0.138	+1.200	<.001	.001	3	11
LARGE_INTESTINE	Myelination in peripheral nervous system →	+0.098	+0.727	.001	<.001	3	11
LARGE_INTESTINE	Peripheral nervous system axon ensheathment →	+0.098	+0.727	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,954 associations by consensus.

Regulation of hippo signaling by NSMAF expression — LIVER

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