NSL1

Across TCGA pan-cancer cohorts, NSL1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NSL1 data layer compared with 28 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher NSL1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated NSL1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and PDAC show a favorable association.

LSCC, PDAC, and OV are the cancer types where NSL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Tertile	All	0.937	0.721	.013	15	view →
PDAC	DFS	Median	IV	0.934	0.250	.024	9	view →
OV	DFS	Median	All	0.873	1.000	.043	4	view →
HNSC	DFS	Median	All	0.306	0.787	.031	4	view →
CCRCC	DFS	Quartile	II,III,IV	0.079	1.000	.036	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NSL1–LSCC (OS)

Open the LSCC breakdown →