NSL1

Across TCGA patient cohorts, NSL1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,856 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NSL1-associated genes across cancer lineages are RFC5, KNTC1, and PRIM1. Each is linked with NSL1 in more than 6 cancer types. Because this analysis shows association rather than direction, both NSL1-to-partner and partner-to-NSL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NSL1 versus RFC5 in LSCC, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NSL1→partner) and Y-score (partner→NSL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RFC5 →	+0.935	+0.384	<.001	<.001	3	7
HNSC	KNTC1 →	+0.997	+0.342	<.001	<.001	3	7
GBM	PRIM1 →	+0.638	+0.390	<.001	<.001	3	7
UCEC	C1orf112 →	+0.730	+0.338	<.001	<.001	3	7
HNSC	PRPSAP2 →	+0.616	+0.176	.002	.003	3	6
LSCC	ANP32E →	+1.024	+0.348	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,856 associations by consensus.

NSL1 vs RFC5 — LSCC

Explore this scatter interactively →