NSG2

Across TCGA cell cohorts, NSG2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,687 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible NSG2-associated GO terms across cancer lineages are Regulation of translational initiation, Golgi organization, and Regulation of macroautophagy. Each is linked with NSG2 in more than 7 cancer types. Because this analysis shows association rather than direction, both NSG2-to-partner and partner-to-NSG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of translational initiation grouped by NSG2-low versus NSG2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NSG2→partner) and Y-score (partner→NSG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of translational initiation →	+0.100	+0.199	<.001	<.001	3	8
LARGE_INTESTINE	Golgi organization →	+0.048	+0.155	<.001	<.001	3	8
LARGE_INTESTINE	Regulation of macroautophagy →	+0.038	+0.111	<.001	.002	2	8
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.073	+0.182	<.001	.001	3	7
UPPER_AERODIGESTIVE_TRACT	Establishment of vesicle localization →	+0.030	+0.122	.001	.001	3	7
SKIN	Mitochondrial electron transport, cytochrome c to oxygen →	+0.065	+0.126	.002	.003	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,687 associations by consensus.

Regulation of translational initiation by NSG2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →