NSG1

Across TCGA patient cohorts, NSG1 mutation is significantly associated with the RNA expression of many other genes, with 830 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NSG1-associated genes across cancer lineages are POM121C, LINC01730, and FRG1HP. Each is linked with NSG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NSG1-to-partner and partner-to-NSG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, POM121C grouped by NSG1-low versus NSG1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NSG1→partner) and Y-score (partner→NSG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	POM121C →	+0.477	+2.439	<.001	.001	3	1
UCEC	LINC01730 →	+0.292	+3.039	.006	<.001	3	1
UCEC	FRG1HP →	+0.490	+2.606	.001	.005	3	1
UCEC	RPS29P32 →	+0.407	+2.406	<.001	<.001	3	1
UCEC	MIR8071-2 →	+0.859	+1.836	.003	.003	3	1
UCEC	MIR8053 →	+0.155	+2.845	.003	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 830 associations by consensus.

POM121C by NSG1 expression — UCEC

Explore this box plot interactively →