NSF

Across TCGA patient cohorts, NSF RNA expression is significantly associated with the protein abundance of many other proteins, with 20,021 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NSF-associated proteins across cancer lineages are RRAS, PSME3, and SPAST. Each is linked with NSF in more than 5 cancer types. Because this analysis shows association rather than direction, both NSF-to-partner and partner-to-NSF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NSF versus RRAS in GBM, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NSF→partner) and Y-score (partner→NSF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RRAS →	-0.505	-0.376	<.001	.002	3	6
LSCC	PSME3 →	+0.391	+0.459	<.001	<.001	3	6
LSCC	SPAST →	+0.437	+0.471	<.001	<.001	3	5
LUAD	CCDC43 →	+0.359	+0.467	<.001	<.001	3	5
GBM	TNFAIP8 →	-0.682	-0.361	<.001	<.001	3	5
GBM	NECAP2 →	-0.289	-0.403	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,021 associations by consensus.

NSF vs RRAS — GBM

Explore this scatter interactively →