NSF

Across TCGA patient cohorts, NSF protein abundance is significantly associated with the RNA expression of many other genes, with 14,372 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NSF-associated genes across cancer lineages are TMSB10, CDCA3, and SERPINH1. Each is linked with NSF in more than 5 cancer types. Because this analysis shows association rather than direction, both NSF-to-partner and partner-to-NSF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NSF versus TMSB10 in BRCA, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NSF→partner) and Y-score (partner→NSF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TMSB10 →	-0.614	-0.264	.002	<.001	3	6
BRCA	CDCA3 →	-0.926	-0.260	<.001	<.001	3	5
GBM	SERPINH1 →	-0.910	-0.452	<.001	<.001	3	5
PDAC	HMGA2 →	-1.087	-0.126	<.001	<.001	3	5
UCEC	CDCA4 →	-0.591	-0.210	.002	<.001	3	5
GBM	TUBB6 →	-0.910	-0.441	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,372 associations by consensus.

NSF vs TMSB10 — BRCA

Explore this scatter interactively →