NSA2

Across TCGA patient cohorts, NSA2 mutation is significantly associated with the RNA expression of many other genes, with 69 significant associations in total. COAD shows the largest number of these associations.

The most reproducible NSA2-associated genes across cancer lineages are RNA5SP457, ARMCX7P, and RNU6-1311P. Each is linked with NSA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NSA2-to-partner and partner-to-NSA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP457 grouped by NSA2-low versus NSA2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NSA2→partner) and Y-score (partner→NSA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNA5SP457 →	+0.463	+3.792	.007	.007	3	1
COAD	ARMCX7P →	+0.134	+4.174	.008	.004	3	1
COAD	RNU6-1311P →	+0.365	+4.308	<.001	.009	3	1
COAD	TXNL4AP1 →	+0.196	+3.951	.005	.005	3	1
COAD	MIR548I1 →	+0.660	+4.129	<.001	.004	3	1
COAD	COX5BP8 →	+0.253	+4.308	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

RNA5SP457 by NSA2 expression — COAD

Explore this box plot interactively →