NSA2

Across TCGA cell cohorts, NSA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,204 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible NSA2-associated GO terms across cancer lineages are Dihydrofolate metabolic process, Positive regulation of endosome organization, and Positive regulation of ligase activity. Each is linked with NSA2 in more than 11 cancer types. Because this analysis shows association rather than direction, both NSA2-to-partner and partner-to-NSA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dihydrofolate metabolic process grouped by NSA2-low versus NSA2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NSA2→partner) and Y-score (partner→NSA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Dihydrofolate metabolic process →	+0.203	+0.875	<.001	<.001	3	12
OVARY	Positive regulation of endosome organization →	-0.076	-0.510	.003	.005	3	8
PANCREAS	Positive regulation of ligase activity →	+0.093	+0.705	.001	<.001	2	9
SKIN	Somatic cell DNA recombination →	+0.068	+0.773	.003	<.001	2	9
SKIN	Somatic diversification of immune receptors via germline recombination within a single locus →	+0.068	+0.773	.003	<.001	2	9
LARGE_INTESTINE	Regulation of phospholipid translocation →	+0.128	+0.575	.002	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,204 associations by consensus.

Dihydrofolate metabolic process by NSA2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →