NRXN2

Across TCGA cell cohorts, NRXN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,444 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible NRXN2-associated GO terms across cancer lineages are Nucleic acid catabolic process, Nucleoside triphosphate biosynthetic process, and Ribonucleoside triphosphate biosynthetic process. Each is linked with NRXN2 in more than 10 cancer types. Because this analysis shows association rather than direction, both NRXN2-to-partner and partner-to-NRXN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleic acid catabolic process grouped by NRXN2-low versus NRXN2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NRXN2→partner) and Y-score (partner→NRXN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Nucleic acid catabolic process →	+0.062	+1.548	<.001	<.001	3	11
OESOPHAGUS	Nucleoside triphosphate biosynthetic process →	+0.125	+1.371	<.001	<.001	3	10
OESOPHAGUS	Ribonucleoside triphosphate biosynthetic process →	+0.135	+1.371	<.001	<.001	3	10
OESOPHAGUS	Purine ribonucleoside triphosphate metabolic process →	+0.109	+1.566	<.001	<.001	3	10
LUNG_SCLC	Epigenetic regulation of gene expression →	+0.059	+2.073	.005	.006	2	11
OESOPHAGUS	RNA catabolic process →	+0.074	+1.553	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,444 associations by consensus.

Nucleic acid catabolic process by NRXN2 expression — OESOPHAGUS

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