NRP2

Across TCGA cell cohorts, NRP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,746 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NRP2-associated GO terms across cancer lineages are Trigeminal ganglion development, Sympathetic neuron projection guidance, and Trunk segmentation. Each is linked with NRP2 in more than 18 cancer types. Because this analysis shows association rather than direction, both NRP2-to-partner and partner-to-NRP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Trigeminal ganglion development grouped by NRP2-low versus NRP2-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NRP2→partner) and Y-score (partner→NRP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Trigeminal ganglion development →	+1.289	+2.177	<.001	<.001	3	19
BLOOD_Lymphoma	Sympathetic neuron projection guidance →	+1.140	+2.643	<.001	<.001	3	19
BLOOD_Lymphoma	Trunk segmentation →	+1.223	+2.781	<.001	<.001	3	18
BLOOD_Lymphoma	Trunk neural crest cell migration →	+1.223	+2.781	<.001	<.001	3	18
BLOOD_Lymphoma	Ventral trunk neural crest cell migration →	+1.223	+2.781	<.001	<.001	3	18
BLOOD_Lymphoma	Vestibulocochlear nerve morphogenesis →	+1.224	+2.788	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,746 associations by consensus.

Trigeminal ganglion development by NRP2 expression — LARGE_INTESTINE

Explore this box plot interactively →