NRK

Across TCGA cell cohorts, NRK RNA expression is significantly associated with the go_rna of many other GO terms, with 1,349 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NRK-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, Heterochromatin organization, and Sodium ion import across plasma membrane. Each is linked with NRK in more than 4 cancer types. Because this analysis shows association rather than direction, both NRK-to-partner and partner-to-NRK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of gene expression, epigenetic grouped by NRK-low versus NRK-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NRK→partner) and Y-score (partner→NRK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of gene expression, epigenetic →	+0.043	+1.087	.001	.008	3	5
SOFT_TISSUE	Heterochromatin organization →	+0.049	+1.144	<.001	.004	3	5
SOFT_TISSUE	Sodium ion import across plasma membrane →	-0.042	-1.016	.003	.008	3	5
SOFT_TISSUE	Heterochromatin formation →	+0.061	+1.563	<.001	.002	3	5
LUNG_NSCLC_LUAD	Spliceosomal tri-snRNP complex assembly →	+0.061	+1.029	<.001	.009	3	4
SOFT_TISSUE	Regulation of mRNA splicing, via spliceosome →	+0.077	+1.204	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,349 associations by consensus.

Negative regulation of gene expression, epigenetic by NRK expression — SOFT_TISSUE

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