NRG4

Across TCGA patient cohorts, NRG4 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,730 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible NRG4-associated proteins across cancer lineages are TSHZ1_S671, MYO1F, and PKN1_T774. Each is linked with NRG4 in more than 3 cancer types. Because this analysis shows association rather than direction, both NRG4-to-partner and partner-to-NRG4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NRG4 versus TSHZ1_S671 in OV, with a Pearson correlation of 0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NRG4→partner) and Y-score (partner→NRG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TSHZ1_S671 →	+0.631	+0.935	.008	.002	3	3
GBM	MYO1F →	-0.508	-0.292	<.001	<.001	3	3
PDAC	PKN1_T774 →	-0.733	-0.705	<.001	<.001	3	3
LSCC	RCN2 →	+0.473	+0.651	<.001	.004	3	3
GBM	ICAM3 →	-0.612	-0.320	<.001	<.001	3	3
PDAC	KCNAB2 →	-0.261	-0.605	.007	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,730 associations by consensus.

NRG4 vs TSHZ1_S671 — OV

Explore this scatter interactively →