NRDE2

Across TCGA cell cohorts, NRDE2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,841 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NRDE2-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, Establishment of RNA localization, and RNA export from nucleus. Each is linked with NRDE2 in more than 18 cancer types. Because this analysis shows association rather than direction, both NRDE2-to-partner and partner-to-NRDE2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of gene expression, epigenetic grouped by NRDE2-low versus NRDE2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NRDE2→partner) and Y-score (partner→NRDE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of gene expression, epigenetic →	+0.077	+0.858	.001	<.001	3	19
LUNG_NSCLC_LUSC	Establishment of RNA localization →	+0.116	+0.832	<.001	.001	3	18
LUNG_NSCLC_LUSC	RNA export from nucleus →	+0.132	+0.762	<.001	.004	2	19
STOMACH	Heterochromatin organization →	+0.075	+0.857	.003	<.001	2	19
STOMACH	Epigenetic regulation of gene expression →	+0.063	+0.721	.001	<.001	3	18
OESOPHAGUS	miRNA processing →	+0.105	+0.787	.005	.002	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,841 associations by consensus.

Negative regulation of gene expression, epigenetic by NRDE2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →