NRBP1

Across TCGA cell cohorts, NRBP1 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NRBP1-associated genes across cancer lineages are PTH, HCN4, and UTF1. Each is linked with NRBP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NRBP1-to-partner and partner-to-NRBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PTH grouped by NRBP1-low versus NRBP1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NRBP1→partner) and Y-score (partner→NRBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	PTH →	+0.023	+6.247	<.001	<.001	3	2
LARGE_INTESTINE	HCN4 →	+0.179	+3.333	<.001	.009	3	1
LARGE_INTESTINE	UTF1 →	+0.015	+3.217	<.001	.006	3	1
LARGE_INTESTINE	ABCG4 →	+0.231	+3.451	.006	.005	3	1
LARGE_INTESTINE	HNRNPCL4 →	+0.047	+3.115	.001	.004	3	1
LARGE_INTESTINE	ADH1A →	+0.188	+3.242	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

PTH by NRBP1 expression — BLOOD_Lymphoma

Explore this box plot interactively →