Across TCGA patient cohorts, NRAP mutation is significantly associated with the total protein of many other genes, with 76 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NRAP-associated genes across cancer lineages are FOXO3a, Tuberin_pT1462, and CD31. Each is linked with NRAP in more than 2 cancer types. Because this analysis shows association rather than direction, both NRAP-to-partner and partner-to-NRAP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NRAP→partner) and Y-score (partner→NRAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FOXO3a →	-0.141	-2.000	.003	.031	3	3
LUAD	Tuberin_pT1462 →	+0.215	+2.700	.006	.006	3	3
LUSC	CD31 →	-0.167	-3.169	.008	.017	3	3
COAD	INPP4B →	-0.495	-3.906	<.001	<.001	3	3
COAD	Claudin-7 →	+0.538	+2.321	.029	.032	3	3
LUSC	EGFR_pY1068 →	+0.444	+2.459	.007	.017	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 76 associations by consensus.

Exploration

NRAP survival (RNA) · tumor vs normal (RNA) · all NRAP data types