NRADDP

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, NRADDP RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated NRADDP data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher NRADDP RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NRADDP expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

KIRC, HNSC, and UCS are the cancer types where NRADDP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCDFSMedianAll0.5300.688<.001117view →
HNSCOSMedianII,III,IV0.7990.687<.00183view →
UCSDFSMedianII,III,IV0.6270.249<.00172view →
UVMOSMedianAll0.7620.421<.00163view →
UCECDFSTertileIV0.7820.292.00236view →
ACCDFSMedianAll0.2810.618<.00136view →
PRADDFSMedianAll0.8320.928<.00126view →
BLCADFSQuartileAll0.7250.400.00222view →
BRCADFSQuartileII,III,IV0.8310.912.01118view →
COADOSQuartileII,III,IV0.6900.913.00315view →
KIRPDFSQuartileIV0.7120.407.01715view →
SKCMDFSMedianIV0.6320.139.00513view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

NRADDP–KIRC (DFS)

Kaplan–Meier survival curve for NRADDP RNA-high vs -low samples in KIRC.

Open the KIRC breakdown →

Exploration