NR5A2

Across TCGA cell cohorts, NR5A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,697 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NR5A2-associated GO terms across cancer lineages are Embryonic cleavage, Maternal-to-zygotic transition of gene expression, and Exocrine pancreas development. Each is linked with NR5A2 in more than 19 cancer types. Because this analysis shows association rather than direction, both NR5A2-to-partner and partner-to-NR5A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Embryonic cleavage grouped by NR5A2-low versus NR5A2-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NR5A2→partner) and Y-score (partner→NR5A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Embryonic cleavage →	-0.319	-1.511	<.001	<.001	3	20
LARGE_INTESTINE	Maternal-to-zygotic transition of gene expression →	-0.330	-1.503	<.001	<.001	3	18
KIDNEY	Exocrine pancreas development →	-0.288	-0.731	<.001	<.001	3	13
LIVER	Positive regulation of glucocorticoid biosynthetic process →	+1.462	+2.714	<.001	<.001	3	10
KIDNEY	Sertoli cell development →	-0.155	-0.758	<.001	.003	3	9
LIVER	Inner cell mass cell differentiation →	+1.688	+3.431	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,697 associations by consensus.

Embryonic cleavage by NR5A2 expression — LARGE_INTESTINE

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