NR5A1

Across TCGA patient cohorts, NR5A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,825 significant associations in total. OV shows the largest number of these associations.

The most reproducible NR5A1-associated GO terms across cancer lineages are Sister chromatid segregation, Mitochondrial gene expression, and Mitochondrial translation. Each is linked with NR5A1 in more than 13 cancer types. Because this analysis shows association rather than direction, both NR5A1-to-partner and partner-to-NR5A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sister chromatid segregation grouped by NR5A1-low versus NR5A1-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NR5A1→partner) and Y-score (partner→NR5A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Sister chromatid segregation →	+0.063	+0.959	<.001	<.001	3	13
STAD	Mitochondrial gene expression →	+0.061	+0.123	<.001	.002	2	14
LUSC	Mitochondrial translation →	+0.029	+0.398	<.001	.008	2	13
SCLC	Establishment of mitotic spindle localization →	+0.096	+0.433	<.001	.001	3	12
THYM	Metaphase chromosome alignment →	+0.072	+1.076	<.001	<.001	3	12
THYM	Mitotic nuclear division →	+0.053	+1.072	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,825 associations by consensus.

Sister chromatid segregation by NR5A1 expression — THYM

Explore this box plot interactively →