NR5A1

Across TCGA cell cohorts, NR5A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,261 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NR5A1-associated GO terms across cancer lineages are Regulation of RNA splicing, Heterochromatin formation, and Regulation of myoblast fusion. Each is linked with NR5A1 in more than 8 cancer types. Because this analysis shows association rather than direction, both NR5A1-to-partner and partner-to-NR5A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of RNA splicing grouped by NR5A1-low versus NR5A1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NR5A1→partner) and Y-score (partner→NR5A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of RNA splicing →	+0.057	+0.051	.002	.001	3	9
BONE	Heterochromatin formation →	+0.075	+0.066	.001	.001	3	8
STOMACH	Regulation of myoblast fusion →	+0.083	+0.052	.006	.005	2	8
BONE	Epigenetic regulation of gene expression →	+0.079	+0.069	<.001	.001	3	7
BONE	Heterochromatin organization →	+0.074	+0.066	<.001	.001	3	7
BONE	Nuclear export →	+0.081	+0.057	.004	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,261 associations by consensus.

Regulation of RNA splicing by NR5A1 expression — BONE

Explore this box plot interactively →