NR4A2

Across TCGA patient cohorts, NR4A2 protein abundance is significantly associated with the RNA expression of many other genes, with 103 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NR4A2-associated genes across cancer lineages are GPR22, GUSBP8, and LINC02886. Each is linked with NR4A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NR4A2-to-partner and partner-to-NR4A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NR4A2 versus GPR22 in OV, with a Pearson correlation of 0.88.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NR4A2→partner) and Y-score (partner→NR4A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GPR22 →	+0.095	+0.817	.002	.007	3	1
OV	GUSBP8 →	+0.459	+0.817	.004	.007	3	1
OV	LINC02886 →	+0.334	+0.817	.005	.007	3	1
OV	PSMA3P1 →	+0.265	+0.817	.003	.007	3	1
OV	SEC23A-AS1 →	+0.329	+0.817	.003	.007	3	1
BRCA	MAGED2 →	+2.020	+1.924	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 103 associations by consensus.

NR4A2 vs GPR22 — OV

Explore this scatter interactively →