NR4A1

Across TCGA patient cohorts, NR4A1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,552 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible NR4A1-associated proteins across cancer lineages are LMNA_S423, TRIM28_S473, and PRPF38B_S529. Each is linked with NR4A1 in more than 7 cancer types. Because this analysis shows association rather than direction, both NR4A1-to-partner and partner-to-NR4A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NR4A1 versus LMNA_S423 in BRCA, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NR4A1→partner) and Y-score (partner→NR4A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LMNA_S423 →	+1.734	+1.741	<.001	<.001	3	8
BRCA	TRIM28_S473 →	+0.711	+1.073	.001	<.001	3	8
CCRCC	PRPF38B_S529 →	-0.740	-1.425	.001	.002	3	7
CCRCC	YJU2_S179 →	+0.942	+1.061	<.001	.002	3	7
LSCC	PHIP_S1315 →	+1.058	+1.251	.001	.008	2	7
OV	PRR14_T363 →	+0.992	+1.173	<.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,552 associations by consensus.

NR4A1 vs LMNA_S423 — BRCA

Explore this scatter interactively →